Dogs can have accidents from time to time. While it might seem simple to wipe up dog pee from tile floors, you want to disinfect the area too. The right cleaner can make the difference in any smell, bacteria, and residue left behind. If your dog still detects the odor, they might think that peeing in that spot is acceptable and will continue to do it. Removing all traces of the pee will keep your house clean and your nose happy.

Fortunately, there are plenty of options on the market today to help banish everything unpleasant about dog urine on tile floors. We gathered our favorites and provided reviews to help you choose the right one for your needs.

A Quick Comparison of Our Favorites of 2023

Image Product Details

Best Overall

Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray

No mixing required

Permanently removes stains and odors

Works on carpets, furniture, fabrics, and upholstery

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Best Value

Nature’s Miracle Dog Urine Destroyer

Enzymatic power

Cuts through dried urine stains to remove them

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Premium Choice

Simple Solution Pet Urine Destroyer

Can tackle various messes

Three-in-one nozzle enables varying saturation levels

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Best for Puppies

Urine Off Dog & Puppy Formula

Enzymes destroy uric acid and urea

Non-toxic formula

Eco-friendly

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Urine Gone Pet Stain & Odor Eliminator

Ideal for multi-pet households

Can be used on several surfaces

Contains enzymes for odor breakdown and elimination

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The 9 Best Tile Floor Cleaners for Dog Urine

  1. Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray — Best Overall

Check Price on HepperThe days when the only way to get rid of nasty pet odors and stains was to open the windows or get rid of your dogs are long gone. That’s why our top pick for the best tile floor cleaners for dog urine goes to the Hepper Advanced Bio-Enzyme Pet Stain and Odor Eliminator Spray.

Not only is does the spray work on tile floors, but it also works and freshens areas such as carpets, furniture, fabrics, upholstery, and anywhere else you need to remove odors and stains.

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The days when the only way to get rid of nasty pet odors and stains was to open the windows or get rid of your dogs are long gone. That’s why our top pick for the best tile floor cleaners for dog urine goes to the Hepper Advanced Bio-Enzyme Pet Stain and Odor Eliminator Spray.

The spray permanently removes stains and odors, though it has been reported that it doesn’t work on every stain. However, with the 100% satisfaction guarantee that comes with the spray, you have nothing to lose by giving it a try. The fact that there’s no mixing required with this product is one of our favorite pluses for this odor eliminator.

We like that it has no scent, although some users reported they’d prefer a scented cleaner.

All in all, this is our overall choice to get rid of those pesky pet stains and odors, all in one fell swoop.

At PetKeen.com, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool cat company!

Pros

Permanently removes stains and odors

Works on carpets, furniture, fabrics, and upholstery

100% satisfaction guarantee

No mixing required

Cons

Comparatively expensive

Some customers may prefer a stronger fragrance

Our best tile floor cleaner for dog urine for the money is Nature’s Miracle Dog Urine Destroyer. With a 128-ounce bottle, you won’t need to worry about having to frequently restock this enzymatic cleaner.

Permanently removes stains and odors

Works on carpets, furniture, fabrics, and upholstery

100% satisfaction guarantee

No mixing required

  • Permanently removes stains and odors
  • Works on carpets, furniture, fabrics, and upholstery
  • 100% satisfaction guarantee
  • No mixing required

Comparatively expensive

Some customers may prefer a stronger fragrance

  • Comparatively expensive
  • Some customers may prefer a stronger fragrance

Size: 128 ounces

Enzymatic: Yes

Check Price on Chewy

This product is perfect for removing the yellow, sticky residue left on tile from pee that dried before you noticed it. It cuts through the urine, eliminating odors and stains and leaving behind a fresh scent. This cleaner can be used on tile, hardwood, fabrics, and carpets. Just spray it on, wait 15 minutes, and blot the stain away.

The smell of this product is overwhelming to some people. It has a strong fragrance that is quite perfumy.

Pros

Enzymatic power

Cuts through dried urine stains to remove them

Cons

Overpowering perfume fragrance

The Simple Solution Pet Urine Destroyer is designed for hard floors. It will quickly and completely remove urine stains from tile, along with any other messes that your dog can make. Muddy paw prints, feces, and vomit stains are no match for this product.

Enzymatic power

Cuts through dried urine stains to remove them

  • Enzymatic power
  • Cuts through dried urine stains to remove them

Overpowering perfume fragrance

  • Overpowering perfume fragrance

Size: 32 ounces

Enzymatic: Yes

The three-in-one nozzle enables you to choose how much product you want to be released. You can choose between foam, spray, and mist. These options allow for different saturation levels, from tough to light stains and messes. The enzymes work to break down the odors, discouraging dogs from repeatedly peeing in the same spot.

However, it may leave your floor slippery after use. There are reports of slick surfaces even after it’s wiped up. The area may need to be rinsed to remove product residue.

Pros

Can tackle various messes

Three-in-one nozzle enables varying saturation levels

Cons

May leave surfaces slippery after use

  1. Urine Off Dog & Puppy Formula — Best for Puppies

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Size: 16.9 ounces

Enzymatic: Yes

This bio-enzymatic Urine Off Dog & Puppy Formula is handy to have around when housebreaking a puppy. It permanently removes urine stains from nearly any surface.

Can tackle various messes

Three-in-one nozzle enables varying saturation levels

  • Can tackle various messes
  • Three-in-one nozzle enables varying saturation levels

May leave surfaces slippery after use

  • May leave surfaces slippery after use

Check Latest Price

Size: 16.9 ounces

Enzymatic: Yes

The enzymes work to break down uric acid, which is responsible for urine’s strong odor. It also eliminates the urea that sticks to surfaces and is typically difficult to remove. It’s safe to use around kids and pets.

Best of all, this cleaner includes no harsh chemicals or bleaches. It’s eco-friendly and has earned the Carpet and Rug Institute’s Seal of Approval, so it’s safe to use on rugs, carpeting, and tile. This is helpful when you have potty-training puppies.

Pros

Enzymes destroy uric acid and urea

Non-toxic formula

Eco-friendly

Cons

Small bottle for the money

Urine Gone Pet Stain & Odor Eliminator is a non-toxic formula that is 100% safe for use around pets. It can be used on tile, carpet, furniture, hardwood, and even litter boxes. This cleaner is ideal for multi-pet households.

Enzymes destroy uric acid and urea

Non-toxic formula

Eco-friendly

  • Enzymes destroy uric acid and urea
  • Non-toxic formula
  • Eco-friendly

Small bottle for the money

  • Small bottle for the money

Size: 24 ounces

Enzymatic: Yes

The enzymes in this cleaner break down urine odor to prevent future peeing in the same spot, completely eliminating all traces of the stain. Some dog owners have even used this in their toilets to remove human urine stains and odors!

Simply sop up liquid from the tile with a paper towel. Then spray this cleaner to cover the affected area, and let sit for a few minutes. Wipe it up, and the stains and smells will be gone.

The biggest issue with this product is its smell. Some dog owners find it to be strong and unpleasant.

Pros

Contains enzymes for odor breakdown and elimination

Ideal for multi-pet households

Can be used on several surfaces

Cons

Some may find the scent to be unpleasant

For removing dog urine from tile floors, Rocco & Roxie Supply Co. Pet Stain & Odor Eliminator will do the job right every time. It can be used on several other surfaces, including carpets, hardwood, furniture, and crate floors.

Contains enzymes for odor breakdown and elimination

Ideal for multi-pet households

Can be used on several surfaces

  • Contains enzymes for odor breakdown and elimination
  • Ideal for multi-pet households
  • Can be used on several surfaces

Some may find the scent to be unpleasant

  • Some may find the scent to be unpleasant

It’s free from bleach and ammonia, making it safe for use around kids and pets. The color-safe formula makes it safe for fabrics too.

The enzymatic bacteria in this formula deeply penetrate stains and feed on ammonia crystals until the stains and odors are completely removed. It leaves behind a pleasant, light fragrance.

To fully remove odors, it’s advised that this product cover the stain and sit for 1 hour before finishing cleaning the area.

Pros

Light scent

Safe for use around kids and pets

Deeply penetrates stains for complete removal

Cons

Must wait up to 1 hour for the product to be fully effective

The OUT! Oxy Fast Activated Pet Stain & Odor Remover can be used on tile, hardwood, carpets, and more. It can even be used to pre-treat laundry before washing it. It works to effectively remove urine, vomit, feces, and blood.

Light scent

Safe for use around kids and pets

Deeply penetrates stains for complete removal

  • Light scent
  • Safe for use around kids and pets
  • Deeply penetrates stains for complete removal

Must wait up to 1 hour for the product to be fully effective

  • Must wait up to 1 hour for the product to be fully effective

 

The oxygen-releasing, powerful formula works to break down and eliminate every part of the stain and remove odors for good. This works on all pet stains. It leaves behind a clean scent so your home remains fresh with no urine odors.

Once this cleaner is applied, it should be wiped up 5–10 minutes later. It can be repeated if necessary until all traces of the stain are gone.

Pros

Multi-surface cleaner

Works with oxygenating power

Clean scent

Cons

May require more than one application

  1. Ion Fusion Severe Pet Urine & Odor Destroyer

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Size: 32 ounces

Enzymatic: Yes

The formula in the Ion Fusion Severe Pet Urine & Odor Destroyer won’t become less potent over time, so you know that the last spray is every bit as effective as the first. As a bonus, this bottle comes with a replacement refill cartridge, giving you 100% more spray.

Multi-surface cleaner

Works with oxygenating power

Clean scent

  • Multi-surface cleaner
  • Works with oxygenating power
  • Clean scent

May require more than one application

  • May require more than one application

This bottle is ergonomically designed to ensure that you get out every last drop, without wasting any product or your money. The ionic formula works to instantly remove stains and odors, leaving behind a mixed berry scent.

The spray is biodegradable and non-toxic, ensuring that it’s safe for use around your family and pets.

Pros

Comes with a refill

Pleasant berry scent

Designed to use every drop

Cons

Some find the scent overwhelming

  1. Angry Orange Pet Stain Remover Spray

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Size: 32 ounces

Enzymatic: Yes

Derived from natural orange peels, Angry Orange Pet Stain Remover Spray is safe for use around animals and people. It’s effective on multiple surfaces, like tile, carpet, hardwood, litter boxes, and grass. The enzyme cleaning power can remove even the toughest stains. It leaves behind the pleasant scent of oranges without being overwhelming.

Comes with a refill

Pleasant berry scent

Designed to use every drop

  • Comes with a refill
  • Pleasant berry scent
  • Designed to use every drop

Some find the scent overwhelming

  • Some find the scent overwhelming

This cleaner ensures up to 80 hours of freshness after use. Once the scent of oranges fades, you’ll be left with a clean, odor-free home. It even works on set-in stains from pee puddles that you may not have noticed until they dried.

While the cleaner is effective at removing stains and odors, it can leave a residue behind on some surfaces. This will need to be wiped with a soapy cloth to remove.

Pros

Smells like oranges

Works on various surfaces

The scent lasts for 80 hours

Cons

May leave residue behind

Buyer’s Guide: Choosing the Best Tile Floor Cleaners for Dog Urine

The cleaner that you choose for your tile floors should be one that works for you and your needs. To choose the right one, here are a few things to keep in mind.

Smells like oranges

Works on various surfaces

The scent lasts for 80 hours

  • Smells like oranges
  • Works on various surfaces
  • The scent lasts for 80 hours

May leave residue behind

  • May leave residue behind

Ingredients

The cleaner that you choose should be one that doesn’t offend your nose. Dogs have a much more sensitive sense of smell than humans do, so if the cleaner bothers you, it probably really bothers your dog. This is a matter of personal preference, but it should also not be a scent that is overwhelming or unpleasant for you.

The enzymes in enzyme cleaners help break down and completely remove odors and stains. This reduces the risk of future accidents in the same place.

Most importantly, the cleaner should be non-toxic and made from as many natural ingredients as possible. You’ll be using this often, so it should be suitable for use around pets and people. No harsh chemicals, like bleaches or ammonia, should be added.

Multi-Purpose

Choosing a cleaner for your tile floor is great, but you don’t want to wind up with several products for different surfaces. That can be time-consuming and wasteful. Many tile floor urine cleaning products are suitable for use on many surfaces.

Some can even work on messes and stains from other pets. This makes them great for homes with several animals and eliminates the need for multiple products. Trying to find the right products for each specific mess and surface can be frustrating when you need to clean up an accident right away.

Price

Figure out how often you’ll have to use the cleaner and what your budget is, so you can choose the right cleaner for your household. If you’re using the cleaner occasionally, you may not need to get something large or expensive. If you’re using the cleaner every day, such as with puppies, it might be best to invest in larger quantities to ensure that you have it on hand when you need it.

Conclusion

Our best overall choice is Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray. We like that it can be used on multiple surfaces and is convenient for multi-pet homes. For the best value, we like the 128-ounce bottle of Nature’s Miracle Dog Urine Destroyer. It has the power to cut through dried stains that you might have missed, thoroughly cleaning and removing them. The Simple Solution Pet Urine Destroyer has a unique three-in-one nozzle to only give you the amount of saturation that you need each time.

We hope that our reviews have helped you decide on the best dog urine cleaner for your tile floor, so you can get the job done right.

Featured Image Credit: Olimpik, Shutterstock