Picture this. You bring home a beautiful and expensive new area rug. After setting it up in your living room, you hear that telltale noise—the sound of your pet starting to vomit. You already know before you reach the living room that they’ve intentionally chosen your rug to vomit on, essentially christening it into your home. You find yourself wondering why you even bother buying nice things if your pets are going to stain them.

Just because you have animals doesn’t mean you need to resign yourself to a home full of pet stains and related odors, though. With the right stain removers in your cleaning supply arsenal, you and your pets can live together in harmony in a beautiful, stain—and odor-free—home.

Keep reading to find our reviews of the best pet stain removers available this year.

A Quick Comparison of Our Favorites of 2023

Image Product Details

Best Overall

Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray

Bio enzymatic formula for optimal odor and stain control

Works for all pet messes

Works in most areas of the home

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Best Value

OUT! Activated Pet Stain Remover

Safe to use on any water-safe surface

Fresh and clean scent

Works well for grass, juice, coffee, and spaghetti sauce stains

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Best Overall

Nature’s Miracle Enzymatic Stain Eliminator

Removes odors

Leaves a fresh scent in its wake

Removes salts and crystals from urine stains

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Zero Odor Pet Stain Remover Spray

Great for multi-pet households

Removes biological stains like urine, feces, and vomit

Doesn’t leave a stench behind

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Nature’s Miracle Stain Destroyer Spray

Fresh scent

Many different applications

Great for stubborn stains

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The 11 Best Pet Stain Removers

  1. Hepper Advanced Bio Enzymatic Pet Stain Odor Eliminator Spray – Best Overall

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Size: 32 ounce bottle

Pet: All Pets

For use on: Carpet, hard floors, furniture, fabrics, etc.

Our pets sometimes slip up and have accidents even after they’re potty trained—it’s just part of the pet-owning process. If you need a handy product to eliminate stains and odors related to pet messes, we absolutely recommend the Hepper Advanced Bio Enzymatic Pet Stain Eliminator Spray. It is incredibly effective without leaving harsh chemicals or strong fragrances behind.

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Size: 32 ounce bottle

Pet: All Pets

For use on: Carpet, hard floors, furniture, fabrics, etc.

Hepper uses a formula that contains bio-enzymatic properties while staying free of harsh additives. You can use this spray virtually anywhere in the home—fabric, upholstery, carpet, you name it. It also has a totally neutral scent not to overwhelm indoor air.

This product is also terrific for aggravating animal bodily fluids like drool, vomit, and poop. It works well on dry spots and wet ones—but it does better with fresh messes than set ones.

We love that it has a 100% money-back guarantee because your pets are of utmost importance to Hepper. If you’re dissatisfied, don’t hesitate to reach out so they can make it right.

At Pet Keen, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool cat company!

100% money-back guarantee

Bio enzymatic formula for optimal odor and stain control

Works for all pet messes

Works in most areas of the home

  • 100% money-back guarantee
  • Bio enzymatic formula for optimal odor and stain control
  • Works for all pet messes
  • Works in most areas of the home

Requires multiple uses for set stains

  • Requires multiple uses for set stains

If you’re on the hunt for the best pet stain remover for the money, this is it. OUT! Oxy Fast Activated Stain and Odor Remover is the most budget-friendly option on our list, but don’t confuse affordability with lower quality. This cleaner features a powerful formulation that uses oxidizing power to remove stubborn and set-in stains and odors. It has been designed for use in a variety of applications such as hardwood floors, litter boxes, and even in your laundry as a pre-treatment for your bedding or clothing.

Size: 32 fluid ounces

Pet: Dogs, cats

For use on: Carpet, hard floors, litter boxes, laundry, water-safe surfaces

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This spray works wonders on urine, vomit, pheromones, blood, and feces. Its formula is very powerful but not chock full of dangerous chemicals. In fact, this cleaner is safe to use in households with both pets and small children.

Safe to use on any water-safe surface

Works well for grass, juice, coffee, and spaghetti sauce stains

Fresh and clean scent

Cleans in as little as five minutes

  • Safe to use on any water-safe surface
  • Works well for grass, juice, coffee, and spaghetti sauce stains
  • Fresh and clean scent
  • Cleans in as little as five minutes

Not for use on wool, silk, or leather

May not work as well on odors

  • Not for use on wool, silk, or leather
  • May not work as well on odors

This extremely high-quality and often raved-about cleaner from Nature’s Miracle Advanced Dog Enzymatic Severe Mess Stain & Odor Eliminator takes the premium spot on our list of the best overall pet stain removers. This cleaner uses an enzymatic formula for biologically based accidents, such as urine, vomit, blood, and feces. It is made specifically with dogs in mind, so it’s best for households with dogs as pets.

Size: 1 gallon

Pet: Dogs

For use on: Carpet, hard floors, furniture, fabrics, etc.

This cleaner is made with patented microbes that work together to discourage your pup from re-soiling the area. It does this by not only removing the stain but any remaining odors that might entice your dog to soil the area again. It has a light and fresh scent that is not too overpowering.

This product can be used on many different surfaces such as concrete, marble, natural stone, ceramic tiles, carpet, furniture, and more.

Removes odors

Removes salts and crystals from urine stains

Leaves a fresh scent in its wake

Simple to use

  • Removes odors
  • Removes salts and crystals from urine stains
  • Leaves a fresh scent in its wake
  • Simple to use

Not as effective on stains from cats and other animals

Cannot be used on untreated hardwood, leather, or suede

  • Not as effective on stains from cats and other animals
  • Cannot be used on untreated hardwood, leather, or suede

Zero Odors’ Stain Removing Spray is another good pick for several reasons. Not only does its powerful surfactants work against even the most stubborn pet messes, but its odor-eliminating formula will bond with the molecules causing odors to create an irreversible reaction to stop even persistent and difficult scents like skunk. Despite its incredibly powerful formulation, this product remains odorless, non-toxic, and is even biodegradable. Its fragrance-free foundation is non-allergenic and non-irritating, so you won’t be replacing stains and odors with something equally harmful in your home.

Size: 16 fluid ounces

Pet: Dogs, cats, other pets

For use on: Carpet, furniture, litter boxes, tile, laminate, hardwood

This simple to use formula is great for dog and cat messes but can work to remove stains caused by other pets, too.

Great for multi-pet households

Doesn’t leave a stench behind

Removes biological stains like urine, feces, and vomit

Safe to use around pets and children

Works fast

  • Great for multi-pet households
  • Doesn’t leave a stench behind
  • Removes biological stains like urine, feces, and vomit
  • Safe to use around pets and children
  • Works fast

Elbow grease necessary to remove stubborn stains

  • Elbow grease necessary to remove stubborn stains

Dog Set-In Stain Destroyer Oxy FormulaNature’s Miracle  is one of the world’s leaders in pet stain and odor removers, and this spray is certainly no exception to that rule. This particular product is designed specifically to remove set-in stains that have been in your home for some time and have proved to be difficult to remove with our stain destroyers.

Size: 32 fluid ounces

Pet: Dogs

For use on: Carpets, hard floors, furniture, fabrics, etc.

This spray has an oxygen-concentrated formula that works to penetrate deep into stains to lift them and any associated odors from your carpet, hard floors, furniture, and fabrics. You can even spray this directly onto soiled clothing before putting it in your washing machine.

It is simple to use, too. All you need to do is saturate the stain with the spray and let it sit for 15 minutes before blotting it up with a clean cloth. The formula has an orange scent to freshen up your space and clothing.

Fresh scent

Many different applications

Great for stubborn stains

Easy to use

Eliminates odors

  • Fresh scent
  • Many different applications
  • Great for stubborn stains
  • Easy to use
  • Eliminates odors

Cannot be used on certain fabrics or flooring

  • Cannot be used on certain fabrics or flooring

If you’re on the hunt for a versatile all-purpose stain remover, theKIDS ‘N’ PETS Instant All-Purpose Stain & Odor Remover is it. This huge jug is a fantastic multi-purpose cleaner that is a must-have for any home with pets or children. It works very well on biological stains such as blood, urine, and feces, and can lift out the associated odors, too.

Size: 1 gallon

Pet: Dogs, cats, kids

For use on: Carpet, hard floors, furniture, fabrics, etc.

The formula uses enzymes to break down the stains and remove odors without leaving a flowery or overpowering scent behind. The enzymatic nature of this cleaner will help to deter pets from soiling in the same spot repeatedly by fully removing all lingering odors. The formula is biodegradable, non-toxic, and mild so it’s gentle enough and safe to use if you have small kids or curious pets roaming about.

This cleaner does not need to be mixed with water, making it very simple to use. All you need to do is shake the bottle, saturate the stain with the formula, allow it to sit for 10 minutes, and then blot the spot with a clean cloth. You may need to repeat these steps for larger messes.

Can be used as a laundry pre-wash

Very versatile in use

Can be used on brick, concrete, and tile

Comes in two different sizes (27 ounces and 1 gallon)

Lightly scented

  • Can be used as a laundry pre-wash
  • Very versatile in use
  • Can be used on brick, concrete, and tile
  • Comes in two different sizes (27 ounces and 1 gallon)
  • Lightly scented

Formula is a little soapy

  • Formula is a little soapy

Simple Solutions’ Extreme Pet Stain & Odor Remover is a powerful enzymatic cleaner that works wonders against urine stains and odors. The enzymes get to work right away to break down, neutralize, and destroy urine stains, but it also works great on feces and vomit. The formula will discourage repeat accidents from occurring in the same spot.

Size: 32 fluid ounces

Pet: Dogs, cats

For use on: Carpets, upholstery, bedding, toys, clothing, water-safe surfaces

This product can be used safely on water-safe surfaces throughout your home, including carpets, furniture, bedding, and clothing. It is safe to use around your children and pets—provided you use it as directed. This formula can be sprayed directly onto stains, poured into a carpet cleaning machine, or even used as a laundry pre-wash.

Easy to use

No rinsing necessary

Powerful against all sorts of stains

Fresh and light scent

  • Easy to use
  • No rinsing necessary
  • Powerful against all sorts of stains
  • Fresh and light scent

May not work as well against strong odors

  • May not work as well against strong odors

This professional-grade stain removing spray Bissell PRO Oxy Stain Destroyer Pet Pretreat Stain Remover Spray, is a powerful formula that uses enzyme agents to lift stains and permanently remove odors. It’s designed to be used as a pre-treatment before a deep cleaning. It can safely be used on carpets and area rugs and is great for use in Bissell cleaning machines.

Size: 22 fluid ounces

Pet: Dogs, cats

For use on: Carpets, upholstery, area rugs

This formula works fast and begins tackling stains in as little as 30 seconds. It works great for removing pet stains like urine, feces, dirt, and blood, but you can also use it for stains like wine, fruit juice, and food grease, making this handy spray one of the most versatile on our list.

Works fast

Fights all types of stains

Easy to use

Can neutralize odors

  • Works fast
  • Fights all types of stains
  • Easy to use
  • Can neutralize odors

Strong smell

Not for use on clothing

Only designed for upholstery and carpets

  • Strong smell
  • Not for use on clothing
  • Only designed for upholstery and carpets

The eco-friendly OdoBan Pet Oxy Stain Remover uses oxygen to help destroy common pet stains like urine, feces, vomit, and even blood. This product has been recognized by the USA EPA Safer Choice Program as its formula contains ingredients that are safe for both human health and the environment. That said, you do need to take safety precautions before using this spray in your home. It may be harmful if inhaled or swallowed so it needs to be kept out of reach of children and pets.

Size: 32 fluid ounces

Pet: Dogs, cats

For use on: Carpet, upholstery, fabric, pet stains, food spills

This spray works very well on stains, but it can also eliminate odors simultaneously. While it doesn’t have an enzymatic formula, it does often work well at odor removal. This may mean your pet will not continue soiling the same spot repeatedly.

Bleach-free

No fragrance

Takes less formula to clean stains

No sticky residue

  • Bleach-free
  • No fragrance
  • Takes less formula to clean stains
  • No sticky residue

Needs to be used in a well-ventilated area

Mist cannot be inhaled

Must take safety precautions

  • Needs to be used in a well-ventilated area
  • Mist cannot be inhaled
  • Must take safety precautions

This eco-friendly ECOS for Pets! Stain & Odor Remover features a powerful plant-based formula that can tackle just about any mess your pet leaves in their wake. The non-toxic formulation is completely safe to use around your pets and children. It’s made with strong enzymes that go to work immediately to lift pet stains and neutralize your home of their associated odors.

Size: 22 fluid ounces

Pet: Cats, dogs, small pets

For use on: Rugs, carpet, upholstery, clothing

This spray can be applied to all colors and fabric types and will work wonders on your carpet and furniture. It is very easy to use and only takes five minutes to begin lifting stains and odors.

Does not need to be diluted

Can be used on pet crates and cages

Natural and safe formulation

Available in two sizes

  • Does not need to be diluted
  • Can be used on pet crates and cages
  • Natural and safe formulation
  • Available in two sizes

Not for use in a washing machine

Fragrance may be too strong for some

Not for use in cleaning machines

  • Not for use in a washing machine
  • Fragrance may be too strong for some
  • Not for use in cleaning machines

11. Wee Away Bird Cage Cleaner

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Size: 1 gallon

Pet: Birds, rabbits, hamsters, reptiles

For use on: Cages, carpets, fabrics

Don’t let the name of this product fool you. The Wee Away Bird Cage Cleaner is more than just a birdcage cleaner. It is a vet-recommended cleaner that can be used safely to remove all sorts of pet stains and messes from a wide variety of animals, including birds, rabbits, hamsters, and even reptiles.

This environmentally-friendly cleaner will remove pet droppings from clothing and carpets. You can even use it to clean up after backyard visitors like wild birds make a mess in your yard.

This product is very simple to use. All you need to do is shake the bottle well, spray it on the soiled surface, leave it on for three minutes and then wipe away. You may need to do some scrubbing on particularly stained areas. You should also give the soiled area a rinse after using this product.

Fragrance-free

Easy to use

Biodegradable formula

No chemicals

  • Fragrance-free
  • Easy to use
  • Biodegradable formula
  • No chemicals

Must be rinsed thoroughly after use

Not for dog or cat stains

Not as versatile as other cleaners

  • Must be rinsed thoroughly after use
  • Not for dog or cat stains
  • Not as versatile as other cleaners

Buyer’s Guide: Selecting The Best Pet Stain Remover

Important Factors to Consider When Finding the Best Pet Stain Removers

There are several factors to consider before buying a pet stain remover. Not every formula will work for the stains you have so it’s important to do some research before diving into your purchase. Keep reading to find what factors you should consider before adding any stain remover into your cleaning arsenal.

Purpose

The most important thing to consider before buying a pet stain remover is what type of stain you’re hoping to remove. Some cleaners on our list are very versatile in use and can fight all types of stains, while others are designed specifically for urine or feces. Some cleaners feature formulas for cat owners, while others are designed with dogs or small pets in mind.

Surface Type

What surface type is it that your pet has soiled? Have they urinated on your brand-new area rug or perhaps used your pile of fresh laundry as a litter box? The stain remover you buy needs to be compatible with the surfaces you’re looking to clean. Some of the formulas above are designed specifically for use on certain types of flooring while others are great for laundry and upholstery. If your pet is known for making messes on all types of surfaces, it’s best to invest in a multi-purpose cleaner that can tackle them all.

Ingredients

Whenever you’re cleaning a pet- or child-friendly home, the ingredients in your cleaners should be at the forefront of your mind. You don’t want to use potentially toxic cleaning agents in your home when there are unpredictable animals or kids at play.

The cleaner you buy should be designated safe for use in pet-friendly homes. It shouldn’t contain any toxic ingredients that can cause harm to your pets if inhaled or ingested. The ASPCA found that household products—like cleaners, laundry detergent, and paint—are one of the most common causes of acute toxicosis in pets. Take the time to read the ingredient list and directions carefully to ensure you’re using the product right and that it won’t be harmful to your pets.

You might also consider if the cleaners are scented. Some have light and fresh scents and others contain stronger fragrances. If you or your pets are scent-sensitive, you’ll want to choose a cleaner that’s unscented or very lightly fragranced to not aggravate your senses.

Application Type

There are several different application methods you can choose between. Pre-mixed and ready-to-use sprays are generally easier and faster to use. There’s no need to dilute the mixture, and they can be sprayed directly onto the soiled area without making too much of a mess elsewhere.

If you’re looking to get the best bang for your buck, you might consider one of the larger jugs. These jugs are a bit more difficult to use, but their large quantity provides great value. If the formula doesn’t require mixing, you can pour it straight from the jug into a spray bottle to make the application easier.

Some of the cleaners can be used in conjunction with carpet cleaning machines to provide even more stain-fighting power.

How Do I Remove Stains from Unfinished Hardwood Floors?

Did you notice any trends amongst the cleaners on our list? Most are not intended for use on untreated and unfinished hardwood floors. When your animal makes a mess on unfinished flooring, the wood allows the liquid to soak in which can cause staining and water damage. When animals urinate on unfinished wood flooring, the urine will not only stain the wood but can leave a lingering scent that’s difficult to remove, too.

To remove a pet stain, you’ll need to pour hydrogen peroxide on it. Give the solution time to soak into your wood. Next, wet a rag with more hydrogen peroxide and place it on top of the stain. Lay a piece of plastic wrap over the rag to keep the area moist and allow the solution time to work. Leave it on overnight. In the morning, remove the rag and plastic wrap to reveal a lighter stain. You may need to continue this process until the stain has been completely removed.

Conclusion

Hepper Advanced Bio Enzymatic Pet Stain Odor Eliminator Spray is the best overall pet stain remover from all of the above reviews. Its enzymatic formula is tough on dog-related stains and can be used on many different surfaces. The OUT! Oxy Fast Activated cleaner provides the best value with its heavy-duty cleaning power in a very affordable package.

Pet owners don’t need to resign themselves to a dirty home. Reclaim yours today with any of the pet stain removers above in your cleaning arsenal.